Ginsenoside Rg3 attenuates tumor angiogenesis via inhibiting bioactivities of endothelial progenitor cells.

@article{Kim2012GinsenosideRA,
  title={Ginsenoside Rg3 attenuates tumor angiogenesis via inhibiting bioactivities of endothelial progenitor cells.},
  author={Jae-Won Kim and Seok-Yun Jung and Yi-Hong Kwon and Jun-Hee Lee and You Mie Lee and Boo-yong Lee and Sang-Mo Kwon},
  journal={Cancer biology & therapy},
  year={2012},
  volume={13 7},
  pages={
          504-15
        }
}
Accumulating evidence suggests that Ginsenoside Rg3 appears to inhibit tumor growth including Lewis lung carcinoma, intestinal adenocarcinomas or B16 melanoma by inhibiting cell proliferation, tumor cell invasion and metastasis. Endothelial progenitor cells (EPCs) appear to play a key role in the growth of early tumors by intervening with the angiogenic switch promoting tumor neovessel formation by producing angiogenic cytokines during tumor progression. This paper reports a novel mechanism of… CONTINUE READING
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Biochemical basis of cancer chemoprevention and/or chemotherapy with ginsenosides (Review).

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