Ginsenoside Rg1 improves fertility and reduces ovarian pathological damages in premature ovarian failure model of mice

@article{He2017GinsenosideRI,
  title={Ginsenoside Rg1 improves fertility and reduces ovarian pathological damages in premature ovarian failure model of mice},
  author={L. He and Lizhen Ling and Tianqin Wei and Y. Wang and Zhengai Xiong},
  journal={Experimental Biology and Medicine},
  year={2017},
  volume={242},
  pages={683 - 691}
}
This study aims to investigate the effect as well as mechanism of ginsenoside Rg1 (Rg1) on premature ovarian failure (POF) induced by d-galactose (d-gal) in mice. C57BL/6 female mice were divided into four groups randomly, which were the saline group, the d-gal group, the d-gal + Rg1 group, and the Rg1 group. Body weight was recorded. Overall ovarian function including estrous cycles, sex hormone secretion, ovarian follicle development, and ovarian morphology was analyzed by H&E staining and… Expand
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