Ginsenoside Rg1 attenuates invasion and migration by inhibiting transforming growth factor-β1-induced epithelial to mesenchymal transition in HepG2 cells.

@article{Yu2015GinsenosideRA,
  title={Ginsenoside Rg1 attenuates invasion and migration by inhibiting transforming growth factor-β1-induced epithelial to mesenchymal transition in HepG2 cells.},
  author={Meiling Yu and Xiaobing Yu and Daohua Guo and Binbin Yu and Li Li and Qiao Liao and Rong Xing},
  journal={Molecular medicine reports},
  year={2015},
  volume={11 4},
  pages={3167-73}
}
Ginseng has become one of the most commonly used alternative herbal medicines and its active component, ginsenoside Rg1, possesses known pharmacological effects, including anticancer properties. However, the effects of ginsenoside Rg1 on metastasis have not been investigated. The present study demonstrated that ginsenoside Rg1 was able to suppress transforming growth factor‑β1 (TGF‑β1)‑induced invasion and migration in HepG2 liver cancer cells. This suppression was associated with the… CONTINUE READING

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