Ginsenoside Rb2 enhances the anti-inflammatory effect of ω-3 fatty acid in LPS-stimulated RAW264.7 macrophages by upregulating GPR120 expression

@inproceedings{Huang2017GinsenosideRE,
  title={Ginsenoside Rb2 enhances the anti-inflammatory effect of ω-3 fatty acid in LPS-stimulated RAW264.7 macrophages by upregulating GPR120 expression},
  author={Qi Huang and Ting Wang and He-Yao Wang},
  booktitle={Acta Pharmacologica Sinica},
  year={2017}
}
Recent studies confirm that chronic low-grade inflammation is closely associated with metabolic syndromes, and anti-inflammatory therapy is a potential approach for treating cardiovascular diseases and type 2 diabetes. Accumulating evidence suggests that GPR120 activation is a feasible solution to ameliorating chronic inflammation and improving glucose metabolism. In this study we investigated whether ginsenoside Rb2 (Rb2), which exhibited regulatory activities in glucose and lipid metabolism… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-8 OF 8 CITATIONS

Therapeutic Potential of Ginsenosides as an Adjuvant Treatment for Diabetes

  • Front. Pharmacol.
  • 2018
VIEW 7 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Cimifugin Inhibits Inflammatory Responses of RAW264.7 Cells Induced by Lipopolysaccharide

  • Medical science monitor : international medical journal of experimental and clinical research
  • 2019
VIEW 1 EXCERPT
CITES METHODS

Curcumin and Curcumol Inhibit NF-κB and TGF-β1/Smads Signaling Pathways in CSE-Treated RAW246.7 Cells

  • Evidence-based complementary and alternative medicine : eCAM
  • 2019
VIEW 1 EXCERPT
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 40 REFERENCES

Free fatty acid receptor GPR 120 is highly expressed in enteroendocrine K cells of the upper small intestine and has a critical role in GIP secretion after fat ingestion

T Tanaka, S Katsuma, +3 authors G Tsujimoto
  • Endocrinology
  • 2015