Ginsenoside Rb1 promotes adipogenesis in 3T3-L1 cells by enhancing PPARgamma2 and C/EBPalpha gene expression.

@article{Shang2007GinsenosideRP,
  title={Ginsenoside Rb1 promotes adipogenesis in 3T3-L1 cells by enhancing PPARgamma2 and C/EBPalpha gene expression.},
  author={Wenbin Shang and Ying Yang and Boren Jiang and Hua Jin and Libin Zhou and Shangquan Liu and Mingdao Chen},
  journal={Life sciences},
  year={2007},
  volume={80 7},
  pages={618-25}
}
Evidence has accumulated that ginseng and its main active constituents, ginsenosides, possess anti-diabetic and insulin-sensitizing properties which may be partly realized by regulating adipocyte development and functions. In the present study, we explored the effect of ginsenoside Rb(1), the most abundant ginsenoside in ginseng root, on adipogenesis of 3T3-L1 cells. We found that with standard differentiation inducers, ginsenoside Rb(1) facilitated adipogenesis of 3T3-L1 preadipocytes in a… CONTINUE READING