Ginsenoside Rb1 inhibits proliferation and inflammatory responses in rat aortic smooth muscle cells.

@article{Li2011GinsenosideRI,
  title={Ginsenoside Rb1 inhibits proliferation and inflammatory responses in rat aortic smooth muscle cells.},
  author={Qun-Yi Li and Li Chen and Wen-Huan Fu and Zhong-Dong Li and Bin Wang and Xiao-jin Shi and Ming-kang Zhong},
  journal={Journal of agricultural and food chemistry},
  year={2011},
  volume={59 11},
  pages={6312-8}
}
Ginsenoside Rb1, a known phytoestrogen, is a major pharmacologically active component in ginseng. The present study was designed to investigate the effect of ginsenoside Rb1 on fetal bovine serum (FBS)-induced proliferation and tumor necrosis factor-α (TNF-α)-evoked inflammatory responses in cultured rat aortic vascular smooth muscle cells (VSMCs). The data showed that Rb1 potently inhibited VSMC proliferation and cell growth induced by 5% FBS. These inhibitory effects were associated with G(1… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Ginsenoside Rb1 attenuates agonist-induced contractile response via inhibition of store-operated calcium entry in pulmonary arteries of normal and pulmonary hypertensive rats.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology • 2015

Similar Papers

Loading similar papers…