Ginsenoside Rb1 ameliorates liver fat accumulation by upregulating perilipin expression in adipose tissue of db/db obese mice

@inproceedings{Yu2015GinsenosideRA,
  title={Ginsenoside Rb1 ameliorates liver fat accumulation by upregulating perilipin expression in adipose tissue of db/db obese mice},
  author={Xizhong Yu and Lifang Ye and Hao Zhang and Juan Zhao and Guoqiang Wang and Chao Qing Guo and Wenbin Shang},
  booktitle={Journal of ginseng research},
  year={2015}
}
BACKGROUND Ginsenoside Rb1 (G-Rb1), the major active constituent of ginseng, improves insulin sensitivity and exerts antidiabetic effects. We tested whether the insulin-sensitizing and antidiabetic effects of G-Rb1 results from a reduction in ectopic fat accumulation, mediated by inhibition of lipolysis in adipocytes. METHODS Obese and diabetic db/db mice… CONTINUE READING