Ginkgolide A, B, and huperzine A inhibit nitric oxide production from rat C6 and human BT325 glioma cells.


AIM To study the effects of ginkgolide A, B (Gin A, Gin B) and huperzine A (Hup A) on nitric oxide (NO) production from cultured astrocytes. METHODS Nitrites in supernatants were measured with Griess assay. RESULTS Hup A 0.001-100 mumol.L-1 time- and concentration-dependently inhibited the NO production from rat C6 astrocytoma cells. The NO production… (More)