Ginkgo biloba leaf extract (EGb 761) enhances catalepsy induced by haloperidol and L-nitroarginine in mice.

@article{Fontana2005GinkgoBL,
  title={Ginkgo biloba leaf extract (EGb 761) enhances catalepsy induced by haloperidol and L-nitroarginine in mice.},
  author={Lu{\'i}s C{\'e}sar Fontana and Aparecida S{\^o}nia de Souza and Elaine Del Bel and R M W Oliveira},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={2005},
  volume={38 11},
  pages={
          1649-54
        }
}
  • Luís César Fontana, Aparecida Sônia de Souza, +1 author R M W Oliveira
  • Published in
    Brazilian journal of medical…
    2005
  • Biology, Medicine
  • Ginkgo biloba extract EGb 761 has been reported to have therapeutic effects which have been attributed to anti-oxidant and free radical-scavenging activities, including a direct action on nitric oxide production. L G-nitro-arginine (L-NOARG), a nitric oxide synthase inhibitor, and haloperidol, a drug that blocks dopamine receptors, are both known to induce catalepsy in rodents. Nitric oxide has been shown to influence dopaminergic transmission in the striatum. The purpose of the present study… CONTINUE READING

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