Ginkgo biloba inhibits bleomycin-induced lung fibrosis in rats.

@article{Iraz2006GinkgoBI,
  title={Ginkgo biloba inhibits bleomycin-induced lung fibrosis in rats.},
  author={Mustafa Iraz and Hasan Erdogan and Mahir Kotuk and Murat Yağmurca and Talat Kılıç and Hilal Ermiş and Ersin Fadıllıoǧlu and Zeki Yıldırım},
  journal={Pharmacological research},
  year={2006},
  volume={53 3},
  pages={
          310-6
        }
}
Oxidative stress has been implicated in the pathogenesis of bleomycin-induced lung fibrosis and many antioxidant agents have been studied for prevention and treatment of the disease in animals and humans. We therefore examined whether Ginkgo biloba (Gb), a flavonoid-rich antioxidant, inhibits bleomycin-induced lung fibrosis in rats. Male Sprague-Dawley rats were given a single dose of bleomycin (2.5 mg/kg, intratracheally) in pulmonary fibrosis groups and saline in controls. First dose of Gb… CONTINUE READING

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