Ginkgo biloba extract protects against mercury(II)-induced oxidative tissue damage in rats.
@article{ener2007GinkgoBE, title={Ginkgo biloba extract protects against mercury(II)-induced oxidative tissue damage in rats.}, author={G. Şener and Ozer Sehirli and Ayfer Tozan and Ayliz Velioğlu-Ovunç and N. Gedik and G. Omurtag}, journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association}, year={2007}, volume={45 4}, pages={ 543-50 } }
Mercury(II) is a highly toxic metal which induces oxidative stress in the body. In this study we aimed to investigate the possible protective effect of Ginkgo biloba (EGb), an antioxidant agent, against experimental mercury toxicity in rat model. Following a single dose of 5mg/kg mercuric chloride (HgCl(2); Hg group) either saline or EGb (150mg/kg) was administered for 5days. After decapitation of the rats trunk blood was obtained and the tissue samples from the brain, lung, liver, and kidney… CONTINUE READING
Topics from this paper
96 Citations
Ginkgo biloba extract reduces naphthalene‐induced oxidative damage in mice
- Chemistry, Medicine
- Phytotherapy research : PTR
- 2007
- 16
Effect of dietary antioxidant on mercuric chloride induced lung toxicity and oxidative stress
- Chemistry
- 2015
- 2
Rutin protects mercuric chloride-induced nephrotoxicity via targeting of aquaporin 1 level, oxidative stress, apoptosis and inflammation in rats.
- Chemistry, Medicine
- Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements
- 2019
- 34
The Protective Effects of Tea Polyphenols and Schisandrin B on Nephrotoxicity of Mercury
- Chemistry, Medicine
- Biological Trace Element Research
- 2011
- 15
Antioxidant potential of hesperidin and ellagic acid on renal toxicity induced by mercuric chloride in rats
- Chemistry
- 2014
- 14
Hepato Ameliorative Effect of Azadirachta indica Leaves Extract against Mercuric Chloride Environmental Pollution.
- Chemistry
- 2010
- 14
Protective effect of Moringa oleifera oil against HgCl2-induced hepato- and nephro-toxicity in rats
- Medicine, Chemistry
- Journal of basic and clinical physiology and pharmacology
- 2017
- 14
Protective effect of diallylsulphide against mercuric chloride-induced hepatic injury in rats
- Medicine
- Human & experimental toxicology
- 2016
- 10
Effects of Lycopene and Proanthocyanidins on Hepatotoxicity Induced by Mercuric Chloride in Rats
- Chemistry, Medicine
- Biological Trace Element Research
- 2011
- 28
Hepatic endogenous defense potential of propolis after mercury intoxication.
- Chemistry, Medicine
- Integrative zoology
- 2008
- 11
References
SHOWING 1-10 OF 41 REFERENCES
Melatonin protects against mercury(II)-induced oxidative tissue damage in rats.
- Chemistry, Medicine
- Pharmacology & toxicology
- 2003
- 114
Lipid peroxidation in rats administrated with mercuric chloride
- Chemistry, Medicine
- Biological Trace Element Research
- 2007
- 97
LIPID PEROXIDATION AND ANTIOXIDANT ENZYME ACTIVITY IN DIFFERENT ORGANS OF MICE EXPOSED TO LOW LEVEL OF MERCURY
- Chemistry, Medicine
- Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes
- 2001
- 156
Mercury-induced H2O2 production and lipid peroxidation in vitro in rat kidney mitochondria.
- Chemistry, Medicine
- Biochemical pharmacology
- 1991
- 153
Studies on Hg(II)-induced H2O2 formation and oxidative stress in vivo and in vitro in rat kidney mitochondria.
- Chemistry, Medicine
- Biochemical pharmacology
- 1993
- 314
Ginkgo biloba affords dose‐dependent protection against 6‐hydroxydopamine‐induced parkinsonism in rats: neurobehavioural, neurochemical and immunohistochemical evidences
- Biology, Medicine
- Journal of neurochemistry
- 2005
- 127
Cardioprotective and anti-oxidant effects of the terpenoid constituents of Ginkgo biloba extract (EGb 761).
- Chemistry, Medicine
- Journal of molecular and cellular cardiology
- 1997
- 211
The effect of Ginkgo biloba extract (EGb 761) on hepatic sinusoidal endothelial cells and hepatic microcirculation in CCl4 rats.
- Medicine
- The American journal of Chinese medicine
- 2004
- 26
Up-regulation of glutathione synthesis in rat kidney by methyl mercury. Relationship to mercury-induced oxidative stress.
- Chemistry, Medicine
- Biochemical pharmacology
- 1995
- 84
Inhibitory effect of the leaf extract of Ginkgo biloba L. on oxidative stress‐induced platelet aggregation
- Chemistry, Medicine
- Biochemistry and molecular biology international
- 1998
- 76