Ginkgo biloba extract improves oxidative organ damage in a rat model of thermal trauma.

@article{akarcan2005GinkgoBE,
  title={Ginkgo biloba extract improves oxidative organ damage in a rat model of thermal trauma.},
  author={Abdullah Şakarcan and Ozer Sehirli and Ayliz Velioglu-Ov{\"u}nç and Feriha Ercan and G{\"o}zde Erkanl and Nursal Gedik and G{\"o}ksel Şener},
  journal={The Journal of burn care \& rehabilitation},
  year={2005},
  volume={26 6},
  pages={
          515-24
        }
}
This study was designed to determine the possible protective effect of Ginkgo biloba extract (EGb) against oxidative organ damage distant from the original burn wound. Under brief ether anesthesia, the shaved dorsum of the rats was exposed to 90 degrees C (burn group) or 25 degrees C (control group) water bath for 10 seconds. EGb (50 mg/kg/day) or saline was administered intraperitoneally immediately and at 12 hours after the burn injury. Rats were decapitated 24 hours after burn injury and… Expand
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Methods Citations
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27 Citations

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Citation Type

The effect of Myrtus communis L. ethanol extract on the small intestine and lungs in experimental thermal burn injury.
TLDR
Mrytus communis extract may be an ideal candidate to be used as an antioxidant adjunct to improve oxidative distant organ damage to limit the systemic inflammatory response and decreasing the recovery time after thermal injury. Expand
Protective effect of Myrtle (Myrtus communis) on burn induced skin injury.
TLDR
Both oral and topical Myrtle extract treatment was found to have protective role in the burn induced oxidative injury, which may be attributed to the potential antioxidant effect of Myrtle. Expand
Lycopene inhibits caspase-3 activity and reduces oxidative organ damage in a rat model of thermal injury.
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TLDR
Halofuginone treatment improved renal functions in late burn group and hepatic functions in early burn group as demonstrated by decreased serum creatinine, blood urea nitrogen, and alanine aminotransferase levels. Expand
The hepatic protective mechanism of Ginkgo biloba extract in rats with obstructive jaundice.
TLDR
GBE mediated the liver protective effect at least in part by suppressing overproduction of ET-1 and NO and restoring a proper balance between ET- 1 and NO to some extent. Expand
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TLDR
It is hypothesised that melatonin restores the redox balance in the gastric mucosa and protects it from burn-induced oxidative injury and should largely be considered as a limiting factor for tissue-damage. Expand
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TLDR
Melatonin could restore liver damage following thermal injury in humans and repaired the pathomorphological lesions and functional disorders using serum markers of liver dysfunction such as cholinesterase and gamma glutamyl transpeptidase, hepatic protein content and malondialdehyde in a burned-rat model. Expand
Ginkgo biloba, a free oxygen radical scavenger, affects inflammatory mediators to diminish the occurrence of experimental myringosclerosis
TLDR
Myringosclerosis was significantly more severe in control and saline groups than in Ginkgo biloba groups, while the levels of nitrite in ginkgo-treated groups were significantly lower than in untreated and saline-treatedgroups, while glutathione peroxidase levels were significantly higher. Expand
Efficacy of topical application of standardized extract of Tragopogon graminifolius in the healing process of experimental burn wounds
TLDR
Considering the antioxidative stress and anti-inflammatory activities of TG, explained by the high content of phenolic compounds of the plant, standardized TG extract could be considered as a natural remedy for the treatment of burn wounds. Expand
Investigation of wound healing activity of Cynara humilis root extracts.
TLDR
It is suggested that C. humilis powder extract could be a promising source for developing drugs against skin burn and exhibited important wound healing effects on time depending manner. Expand
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