Ginkgo biloba extract ameliorates gentamicin-induced nephrotoxicity in rats.

@article{Naidu2000GinkgoBE,
  title={Ginkgo biloba extract ameliorates gentamicin-induced nephrotoxicity in rats.},
  author={Madireddy Umamaheshwar Rao Naidu and A A Shifow and K. Vijay Kumar and Kamaraju Suguna Ratnakar},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year={2000},
  volume={7 3},
  pages={
          191-7
        }
}
The effect of Ginkgo biloba (EGb), a plant extract with an antioxidant effect, has been studied on gentamicin-induced nephrotoxicity in male wistar rats. Ginkgo biloba extract (300 mg/kg BW) was administered orally 2 days before and 8 days concurrently with gentamicin (80 mg/kg BW). Saline treated animals served as control. Estimations of urine creatinine, glucose, blood urea, serum creatinine, plasma and kidney tissue MDA were carried out after 8 days of gentamicin treatment. Kidneys were… Expand
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  • Medicine
  • The American journal of Chinese medicine
  • 2004
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Treatment with N. sativa oil produced a dose-dependent amelioration of the biochemical and histological indices of GM nephrotoxicity that was statistically significant at the two higher doses used. Expand
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  • Chemistry, Medicine
  • Phytomedicine : international journal of phytotherapy and phytopharmacology
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The results indicate that the three antioxidants and amrinone have potential protective effects against vancomycin-induced nephrotoxicity, which might in part be due to inhibition of free oxygen radical production. Expand
Precautionary Effect of Ginkgo biloba Against Mercury-Induced Acute Nephro-Hepatotoxicity in male Rats
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