Ginkgo biloba Extract Reduces Hippocampus Inflammatory Responses, Improves Cardiac Functions And Depressive Behaviors In A Heart Failure Mouse Model

@article{Zhang2019GinkgoBE,
  title={Ginkgo biloba Extract Reduces Hippocampus Inflammatory Responses, Improves Cardiac Functions And Depressive Behaviors In A Heart Failure Mouse Model},
  author={Li-jun Zhang and Jianyang Liu and Ying-Bin Ge and Meiyan Liu},
  journal={Neuropsychiatric Disease and Treatment},
  year={2019},
  volume={15},
  pages={3041 - 3050}
}
Background Depression has been shown to share an extremely high comorbidity with heart failure (HF). Ginkgo biloba extract (GBE) is a widely used traditional Chinese medicine in cardiac disease. However, its potential therapeutic effect on depressive symptoms following HF largely remains unknown. In this article, we aimed to investigate its effects in reducing depressive behaviors of a HF mouse model. Moreover, we also discussed whether its effects are associated with changes in neural… Expand
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This review will give a brief overview about preclinical models, presenting the heterogeneity of tinnitus sub-types depending on the different inner ear and brain structures involved in tinnitis etiology and pathogenesis, and providing an extensive overview on preclinical drug-based therapeutic approaches that have been explored in various animal models. Expand
TCM Substances in Neuropsychopharmacotherapy

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