Ginkgo biloba Extract (GbE) Stimulates the Hypothalamic Serotonergic System and Attenuates Obesity in Ovariectomized Rats

  title={Ginkgo biloba Extract (GbE) Stimulates the Hypothalamic Serotonergic System and Attenuates Obesity in Ovariectomized Rats},
  author={R. M. Banin and I. S. de Andrade and S. M. Cerutti and L. Oyama and M. Telles and E. Ribeiro},
  journal={Frontiers in Pharmacology},
  • R. M. Banin, I. S. de Andrade, +3 authors E. Ribeiro
  • Published 2017
  • Medicine
  • Frontiers in Pharmacology
  • Menopause is associated with increased risk to develop obesity but the mechanisms involved are not fully understood. We have shown that Ginkgo biloba extract (GbE) improved diet-induced obesity. Since GbE might be effective in the treatment of obesity related to menopause, avoiding the side effects of hormone replacement therapy, we investigated the effect of GbE on hypothalamic systems controlling energy homeostasis. Wistar rats were either ovariectomized (OVX) or Sham-operated. After 2 months… CONTINUE READING
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