Gingival Fibroblasts as a Promising Source of Induced Pluripotent Stem Cells

@inproceedings{Egusa2010GingivalFA,
  title={Gingival Fibroblasts as a Promising Source of Induced Pluripotent Stem Cells},
  author={Hiroshi Egusa and Keisuke Okita and Hiroki Kayashima and Guannan Yu and Sho Fukuyasu and Makio Saeki and Takuya Matsumoto and Shinya Yamanaka and Hirofumi Yatani},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND Induced pluripotent stem (iPS) cells efficiently generated from accessible tissues have the potential for clinical applications. Oral gingiva, which is often resected during general dental treatments and treated as biomedical waste, is an easily obtainable tissue, and cells can be isolated from patients with minimal discomfort. METHODOLOGY/PRINCIPAL FINDINGS We herein demonstrate iPS cell generation from adult wild-type mouse gingival fibroblasts (GFs) via introduction of four… CONTINUE READING
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A smallmolecule approach to bone regenerative medicine in dentistry

H Egusa, M Saeki, M Doi, S Fukuyasu, T Matsumoto
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