Gingival Fibroblasts as a Promising Source of Induced Pluripotent Stem Cells

  title={Gingival Fibroblasts as a Promising Source of Induced Pluripotent Stem Cells},
  author={Hiroshi Egusa and Keisuke Okita and Hiroki Kayashima and Guannan Yu and Sho Fukuyasu and Makio Saeki and Takuya Matsumoto and Shinya Yamanaka and Hirofumi Yatani},
  booktitle={PloS one},
BACKGROUND Induced pluripotent stem (iPS) cells efficiently generated from accessible tissues have the potential for clinical applications. Oral gingiva, which is often resected during general dental treatments and treated as biomedical waste, is an easily obtainable tissue, and cells can be isolated from patients with minimal discomfort. METHODOLOGY/PRINCIPAL FINDINGS We herein demonstrate iPS cell generation from adult wild-type mouse gingival fibroblasts (GFs) via introduction of four… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS


Publications citing this paper.
Showing 1-10 of 50 extracted citations

iPS Cells—The Triumphs and Tribulations

Dentistry journal • 2016
View 4 Excerpts
Highly Influenced

Human Gingival Integration-Free iPSCs; a Source for MSC-Like Cell

International journal of molecular sciences • 2015
View 7 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 50 references

A smallmolecule approach to bone regenerative medicine in dentistry

H Egusa, M Saeki, M Doi, S Fukuyasu, T Matsumoto
J Oral Biosci • 2010
View 1 Excerpt

Similar Papers

Loading similar papers…