Ginger ingredients reduce viability of gastric cancer cells via distinct mechanisms.

@article{Ishiguro2007GingerIR,
  title={Ginger ingredients reduce viability of gastric cancer cells via distinct mechanisms.},
  author={Kazuhiro Ishiguro and Takafumi Ando and Osamu Maeda and Naoki Ohmiya and Yasumasa Niwa and Kenji Kadomatsu and Hidemi Goto},
  journal={Biochemical and biophysical research communications},
  year={2007},
  volume={362 1},
  pages={
          218-23
        }
}
Ginger has been used throughout the world as spice, food and traditional herb. We found that 6-gingerol, a phenolic alkanone isolated from ginger, enhanced the TRAIL-induced viability reduction of gastric cancer cells while 6-gingerol alone affected viability only slightly. 6-Gingerol facilitated TRAIL-induced apoptosis by increasing TRAIL-induced caspase-3/7 activation. 6-Gingerol was shown to down-regulate the expression of cIAP1, which suppresses caspase-3/7 activity, by inhibiting TRAIL… CONTINUE READING
Highly Cited
This paper has 54 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 46 citations

54 Citations

0510'10'13'16'19
Citations per Year
Semantic Scholar estimates that this publication has 54 citations based on the available data.

See our FAQ for additional information.