Furthermore, at present it remains unclear whether blocking the Ashwell receptor— for instance, with synthetic high-affinity ligands—may diminish thrombocytopenia once full-blown DIC has developed and whether this could have a beneficial effect in severe sepsis. 1. Ashwell, G. & Harford, J. Annu. Rev. Biochem. 51, 531–554 (1982). 2. Grewal, P.K. et al. Nat… (More)
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