Gilbert's syndrome: High frequency of the (TA)7 TAA allele in India and its interaction with a novel CAT insertion in promoter of the gene for bilirubin UDP-glucuronosyltransferase 1 gene.

@article{Farheen2006GilbertsSH,
  title={Gilbert's syndrome: High frequency of the (TA)7 TAA allele in India and its interaction with a novel CAT insertion in promoter of the gene for bilirubin UDP-glucuronosyltransferase 1 gene.},
  author={Shabana Farheen and Sanghamitra Sengupta and Amal Kumar Santra and Suparna Pal and Gopal Krishna Dhali and Meenakshi Chakravorty and Partha Majumder and Abhijit Chowdhury},
  journal={World journal of gastroenterology},
  year={2006},
  volume={12 14},
  pages={2269-75}
}
AIM To identify the variants in UDP-glucuronosyltransferase 1 (UGT1A1) gene in Gilbert's syndrome (GS) and to estimate the association between homozygosity for TA insertion and GS in India, as well as the frequency of TA insertion and its impact among normal controls in India. METHODS Ninety-five GS cases and 95 normal controls were selected. Liver function and other tests were done. The promoter and all 5 exons of UGT1A1 gene were resequenced. Functional assessment of a novel trinucleotide… CONTINUE READING
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