Gigadalton-scale shape-programmable DNA assemblies

@article{Wagenbauer2017GigadaltonscaleSD,
  title={Gigadalton-scale shape-programmable DNA assemblies},
  author={Klaus F. Wagenbauer and Christian Sigl and Hendrik Dietz},
  journal={Nature},
  year={2017},
  volume={552},
  pages={78-83}
}
Natural biomolecular assemblies such as molecular motors, enzymes, viruses and subcellular structures often form by self-limiting hierarchical oligomerization of multiple subunits. Large structures can also assemble efficiently from a few components by combining hierarchical assembly and symmetry, a strategy exemplified by viral capsids. De novo protein design and RNA and DNA nanotechnology aim to mimic these capabilities, but the bottom-up construction of artificial structures with the… Expand
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