Giardia duodenalis mouse model for the development of novel antigiardial agents.

@article{Abraham2018GiardiaDM,
  title={Giardia duodenalis mouse model for the development of novel antigiardial agents.},
  author={Rebecca J. Abraham and Mark O'Dea and Bertha Rusdi and Stephen W Page and Ryan M O'Handley and Sam Abraham},
  journal={Journal of microbiological methods},
  year={2018},
  volume={145},
  pages={7-9}
}
This study describes a neonatal mouse model of Giardia infection for development of novel antigiardials. Mice were infected with the axenically cultured Assemblage A BAH2c2 strain, with 105 trophozoites per animal recovered. This model proved to be robust and consistent for use in preliminary drug efficacy trials and drug development.