Giant viruses: conflicts in revisiting the virus concept.

  title={Giant viruses: conflicts in revisiting the virus concept.},
  author={Patrick Forterre},
  volume={53 5},
The current paradigm on the nature of viruses is based on early work of the 'phage group' (the pro-phage concept) and molecular biologists working on tumour viruses (the proto-oncogene concept). It posits that viruses evolved from either prokaryotic or eukaryotic cellular genes that became infectious via their association with capsid genes. In this view, after their emergence viruses continued to evolve by stealing cellular genes (the escape model). This paradigm has been challenged recently by… CONTINUE READING


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