Giant-cell tumor of bone with pulmonary metastases. Six case reports and a review of the literature.

@article{Bertoni1988GiantcellTO,
  title={Giant-cell tumor of bone with pulmonary metastases. Six case reports and a review of the literature.},
  author={Franco Bertoni and David A. Present and Alessandra Sudanese and Nicola Baldini and Patrizia Bacchini and Mario Campanacci},
  journal={Clinical orthopaedics and related research},
  year={1988},
  volume={237},
  pages={275-85}
}
Giant-cell tumor of bone rarely metastasizes to the lung. In three of six cases, lesions in lung tissue were histologically benign. In 39 such cases reported in the literature, the treatments were surgical extirpation, chemotherapy, and radiation therapy. Resection was indicated to definitely diagnose the pulmonary lesions as benign giant-cell tumors. Radiation therapy and/or chemotherapy may be beneficial as adjuvant treatment, especially where the lesions are anatomically inaccessible. Some… CONTINUE READING