Giant cell fibroblastoma in a 4-year-old boy: a case report and review of the literature.

Abstract

Giant cell fibroblastoma (GCF) is a rare type of fibroblastic tumor, first described as a juvenile form of dermatofibrosarcoma. Although recurrences are common after local surgical resection, metastasis is not reported.We report a case of a 4-year-old boy with giant cell fibroblastoma, in which the neoplasm was characterized histologically by a proliferation of spindle-shaped cells intermixed with pseudovascular channels called "angiectold spaces". The spaces were lined by large cells with pleomorphic nuclei intermixed with multinucleated cells. Immunohistochemically, the tumor stained diffusely for vimentin and CD34, but negative for S 100 protein. Since the initial description in 1982, less than 100 cases of GCF have been reported. This patient's presentation is particularly interesting because present the first case reported in Bosnia and Herzegovina.

Cite this paper

@article{Dori2006GiantCF, title={Giant cell fibroblastoma in a 4-year-old boy: a case report and review of the literature.}, author={Mirsad Dori{\'c} and Svjetlana Radovi{\'c} and Mirsad Babi{\'c} and Suada Kuskunovi{\'c} and Ivana Tomic and Ajna Huki{\'c} and Ivan Selak}, journal={Medicinski arhiv}, year={2006}, volume={60 6}, pages={389-90} }