GiRaF: robust, computational identification of influenza reassortments via graph mining

@inproceedings{Nagarajan2011GiRaFRC,
  title={GiRaF: robust, computational identification of influenza reassortments via graph mining},
  author={Niranjan Nagarajan and Carleton L. Kingsford},
  booktitle={Nucleic acids research},
  year={2011}
}
Reassortments in the influenza virus--a process where strains exchange genetic segments--have been implicated in two out of three pandemics of the 20th century as well as the 2009 H1N1 outbreak. While advances in sequencing have led to an explosion in the number of whole-genome sequences that are available, an understanding of the rate and distribution of reassortments and their role in viral evolution is still lacking. An important factor in this is the paucity of automated tools for confident… CONTINUE READING
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