Gi alpha 3 and G(o) alpha selectively associate with the cloned somatostatin receptor subtype SSTR2.

@article{Law1993GiA3,
  title={Gi alpha 3 and G(o) alpha selectively associate with the cloned somatostatin receptor subtype SSTR2.},
  author={Susan F Law and Kazuto Yasuda and Graeme I. Bell and Terry David Reisine},
  journal={The Journal of biological chemistry},
  year={1993},
  volume={268 15},
  pages={10721-7}
}
The interaction of the SRIF receptor subtype SSTR2 with pertussis toxin-sensitive G proteins was investigated using an immunoprecipitation approach employing peptide-directed antisera against Gi alpha and G(o) alpha. Antisera directed against either the COOH terminus of Gi alpha or Go alpha uncoupled SSTR2-G protein complexes from CHO cells stably expressing the cloned receptor indicating that both G proteins form complexes with SSTR2. Chinese hamster ovary cells primarily express Gi alpha 3… CONTINUE READING