Ghrelin is released from rat hypothalamic explants and stimulates corticotrophin-releasing hormone and arginine-vasopressin.

@article{Mozid2003GhrelinIR,
  title={Ghrelin is released from rat hypothalamic explants and stimulates corticotrophin-releasing hormone and arginine-vasopressin.},
  author={Abdul M Mozid and Giuseppe Tringali and Mary L. Forsling and Megan Hendricks and Sharon J. Ajodha and Richard Edwards and Pierluigi Navarra and Ashley B. Grossman and M{\'a}rta Korbonits},
  journal={Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme},
  year={2003},
  volume={35 8},
  pages={455-9}
}
Ghrelin and synthetic growth hormone secretagogues have diverse effects on the hypothalamus including effects on appetite and the growth hormone axis as well as on the hypothalamus-pituitary-adrenal (HPA) axis. We previously studied the effect of synthetic growth hormone secretagogues on CRH and AVP release from rat hypothalami in vitro, and now report on the effects of ghrelin on CRH and AVP release. The ghrelin protein content and ghrelin output from rat hypothalamic explants was measured… CONTINUE READING
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