Ghrelin inhibits steroid biosynthesis by cultured granulosa-lutein cells.

  title={Ghrelin inhibits steroid biosynthesis by cultured granulosa-lutein cells.},
  author={Isabella Viani and Alessandra Vottero and Francesco Tassi and Giulia Cremonini and Chiara Sartori and S Bernasconi and Bruno L Ferrari and Lucia Ghizzoni},
  journal={The Journal of clinical endocrinology and metabolism},
  volume={93 4},
CONTEXT Growing evidence indicates that ghrelin may participate in the regulation of different aspects of reproductive function. The genes encoding for this peptide and its receptor are expressed in the human ovary, but their functional role is still unknown. OBJECTIVE The aim of our study was to assess whether ghrelin has any effect on steroid synthesis by human granulosa-lutein cells and to identify the receptor isoform through which this potential effect is exerted. DESIGN, PATIENTS, AND… CONTINUE READING
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