Ghrelin inhibits apoptosis induced by high glucose and sodium palmitate in adult rat cardiomyocytes through the PI3K-Akt signaling pathway.

@article{Kui2009GhrelinIA,
  title={Ghrelin inhibits apoptosis induced by high glucose and sodium palmitate in adult rat cardiomyocytes through the PI3K-Akt signaling pathway.},
  author={Liu Kui and Zhang Weiwei and Liu Ling and He Daikun and Zhou Guoming and Zhou Linuo and Hu Renming},
  journal={Regulatory peptides},
  year={2009},
  volume={155 1-3},
  pages={62-9}
}
OBJECTIVE Ghrelin is a gastric acyl-peptide that has been identified as an endogenous ligand for the growth hormone secretagogue receptor. It has been reported to have cardioprotective activities independent of growth hormone release. We investigated the effect of ghrelin on apoptosis induced by high glucose and sodium palmitate and the mechanisms underlying the cardioprotective activities of ghrelin. RESEARCH DESIGN AND METHODS Cardiomyocytes were isolated from hearts of adult rats and… CONTINUE READING
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