Ghrelin improves burn-induced delayed gastrointestinal transit in rats.

@article{Sallam2007GhrelinIB,
  title={Ghrelin improves burn-induced delayed gastrointestinal transit in rats.},
  author={Hanaa S. Sallam and Hermes Murtha Oliveira and Hua Tian Gan and David Newcomb Herndon and Jiande D. Z. Chen},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2007},
  volume={292 1},
  pages={
          R253-7
        }
}
Delayed gastrointestinal transit is common in patients with severe burn. Ghrelin is a potent prokinetic peptide. We aimed at testing the effect of ghrelin on burn-induced delayed gastrointestinal transit in rats. Gastric emptying (GE), intestinal transit (IT), and colonic transit (CT) studies were performed in male Sprague-Dawley rats. Rats were randomized into two main groups as follows: sham injury and ghrelin-treated burn injury with doses of 0, 2, 5, and 10 nmol/rat ip 6 h after burn. Sham… CONTINUE READING

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