Ghrelin gene expression is markedly higher in fetal pancreas compared with fetal stomach: effect of maternal fasting.

@article{Chanoine2004GhrelinGE,
  title={Ghrelin gene expression is markedly higher in fetal pancreas compared with fetal stomach: effect of maternal fasting.},
  author={J. P. Chanoine and Alfred K. Wong},
  journal={Endocrinology},
  year={2004},
  volume={145 8},
  pages={3813-20}
}
Ghrelin is an orexigenic peptide secreted mainly by the stomach in adult rats. Ghrelin concentrations increase with fasting and decrease after food intake. Ghrelin is also present in the placenta and in the fetal stomach, but the role of fetal ghrelin remains unclear. In this study, we compared changes in plasma ghrelin, insulin, and glucose concentrations and in ghrelin gene expression in stomach, pancreas, and placenta in response to fasting and feeding in adult nonpregnant rats and in 20-d… CONTINUE READING

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