Ghrelin and appetite control in humans--potential application in the treatment of obesity.

Abstract

Ghrelin is a peptide hormone secreted into circulation from the stomach. It has been postulated to act as a signal of hunger. Ghrelin administration acutely increases energy intake in lean and obese humans and chronically induces weight gain and adiposity in rodents. Circulating ghrelin levels are elevated by fasting and suppressed following a meal… (More)
DOI: 10.1016/j.peptides.2011.07.021

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