Ghrelin Indirectly Activates Hypophysiotropic CRF Neurons in Rodents

@inproceedings{Cabral2012GhrelinIA,
  title={Ghrelin Indirectly Activates Hypophysiotropic CRF Neurons in Rodents},
  author={Agustina Cabral and Olga Suescun and Jeffrey M Zigman and Mario Perello},
  booktitle={PloS one},
  year={2012}
}
Ghrelin is a stomach-derived hormone that regulates food intake and neuroendocrine function by acting on its receptor, GHSR (Growth Hormone Secretagogue Receptor). Recent evidence indicates that a key function of ghrelin is to signal stress to the brain. It has been suggested that one of the potential stress-related ghrelin targets is the CRF (Corticotropin-Releasing Factor)-producing neurons of the hypothalamic paraventricular nucleus, which secrete the CRF neuropeptide into the median… CONTINUE READING

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