Ghrelin—a hormone with multiple functions

  title={Ghrelin—a hormone with multiple functions},
  author={M. Korbonits and A. P. Goldstone and M. Gueorguiev and A. Grossman},
  journal={Frontiers in Neuroendocrinology},
  • M. Korbonits, A. P. Goldstone, +1 author A. Grossman
  • Published 2004
  • Biology, Medicine
  • Frontiers in Neuroendocrinology
  • The growth hormone secretagogue ghrelin is in the centre of interest since its discovery in 1999. It stimulates growth hormone, corticotropic hormone and prolactin secretion, but also plays an important role in the regulation of appetite, carbohydrate- and lipid metabolism and possibly on gastric acid secretion, gastric motility, heart function and as well as immune functions and cell proliferation. Ghrelin was originally identified from the stomach but it is also present in all tissue among… CONTINUE READING
    379 Citations
    Ghrelin: a new peptide regulating growth hormone release and food intake.
    • 76
    Ghrelin's role as a major regulator of appetite and its other functions in neuroendocrinology.
    • 32
    Structure and Physiological Actions of Ghrelin
    • 134
    • PDF
    Ghrelin: A potential therapeutic target for cancer
    • 50
    Ghrelin: a metabolic signal affecting the reproductive system.
    • 62


    The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans.
    • 1,297
    • PDF
    Expression of ghrelin and of the GH secretagogue receptor by pancreatic islet cells and related endocrine tumors.
    • 360
    • PDF
    Immunolocalization of ghrelin and its functional receptor, the type 1a growth hormone secretagogue receptor, in the cyclic human ovary.
    • 222
    • PDF
    Ghrelin induces adiposity in rodents
    • 3,648
    Inhibitory effect of ghrelin on insulin and pancreatic somatostatin secretion.
    • 283
    • PDF