Getting to the site of inflammation: the leukocyte adhesion cascade updated

@article{Ley2007GettingTT,
  title={Getting to the site of inflammation: the leukocyte adhesion cascade updated},
  author={Klaus Ley and Carlo Laudanna and Myron I. Cybulsky and Sussan Nourshargh},
  journal={Nature Reviews Immunology},
  year={2007},
  volume={7},
  pages={678-689}
}
Neutrophil recruitment, lymphocyte recirculation and monocyte trafficking all require adhesion and transmigration through blood-vessel walls. The traditional three steps of rolling, activation and firm adhesion have recently been augmented and refined. Slow rolling, adhesion strengthening, intraluminal crawling and paracellular and transcellular migration are now recognized as separate, additional steps. In neutrophils, a second activation pathway has been discovered that does not require… 

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