Getting the Hologenome Concept Right: an Eco-Evolutionary Framework for Hosts and Their Microbiomes

@inproceedings{Theis2016GettingTH,
  title={Getting the Hologenome Concept Right: an Eco-Evolutionary Framework for Hosts and Their Microbiomes},
  author={Kevin R Theis and Nolwenn M Dheilly and Jonathan L. Klassen and Robert M Brucker and John F Baines and Thomas C G Bosch and John F Cryan and Scott F. Gilbert and Charles J Goodnight and Elisabeth A. Lloyd and Jan Sapp and Philippe Vandenkoornhuyse and Ilana Zilber-Rosenberg and Eugene Rosenberg and Seth R Bordenstein},
  booktitle={mSystems},
  year={2016}
}
Given the complexity of host-microbiota symbioses, scientists and philosophers are asking questions at new biological levels of hierarchical organization-what is a holobiont and hologenome? When should this vocabulary be applied? Are these concepts a null hypothesis for host-microbe systems or limited to a certain spectrum of symbiotic interactions such as host-microbial coevolution? Critical discourse is necessary in this nascent area, but productive discourse requires that skeptics and… CONTINUE READING
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