Get receptive to metabotropic glutamate receptors.

  title={Get receptive to metabotropic glutamate receptors.},
  author={Jean-Philippe Pin and J{\"o}el Bockaert},
  journal={Current opinion in neurobiology},
  volume={5 3},
Glutamate activates not only ionotropic glutamate receptors, but also G-protein-coupled receptors, called metabotropic glutamate receptors. Recent studies have revealed that these metabotropic receptors share distinctive structural properties and that they form a subgroup within the heptahelical receptor family. The development of ligands that bind specifically to these receptors has provided a means of characterizing the important roles they play in the tuning of fast synaptic transmission… CONTINUE READING


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