• DOI:10.3109/00016348609157380
Corpus ID: 9229704

Gestrinone (R2323) Binding to Steroid Receptors in Human Uterine Endometrial Cytosol

@article{Tamaya1986GestrinoneB,
  title={Gestrinone (R2323) Binding to Steroid Receptors in Human Uterine Endometrial Cytosol},
  author={T. Tamaya and J. Fujimoto and Y. Watanabe and K. Arahori and H. Okada},
  journal={Acta Obstetricia et Gynecologica Scandinavica},
  year={1986},
  volume={65}
}

T. Tamaya, J. Fujimoto, +2 authors H. Okada

Published 1986

Medicine

Acta Obstetricia et Gynecologica Scandinavica

To understand the mechanism of biological action of gestrinone (R2323), which has a therapeutic effect against endometriosis, the binding of gestrinone to numerous classes of intracellular steroid binding proteins was studied in the human uterine endometrium. Gestrinone bound to endometrial receptors for estrogen, progesterone and androgen, but seemed not to bind to endometrial intracellular corticosteroid‐binding globulin and sex hormone‐binding globulin. Gestrinone occupies all specific… CONTINUE READING

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