Gestational diabetes and the risk of breast cancer among women in the Jerusalem Perinatal Study

@article{Perrin2007GestationalDA,
  title={Gestational diabetes and the risk of breast cancer among women in the Jerusalem Perinatal Study},
  author={Mary C. Perrin and Mary Beth Terry and Karine Kleinhaus and Lisa Deutsch and Rivka Yanetz and Efrat Tiram and Ronit Calderon-Margalit and Yechiel Friedlander and Ora Paltiel and Susan Harlap},
  journal={Breast Cancer Research and Treatment},
  year={2007},
  volume={108},
  pages={129-135}
}
Gestational diabetes is becoming increasingly common; it is important to determine how it relates to future risk of disease. We investigated the relation of gestational diabetes to breast cancer in 37,926 women who had one or more live births in 1964–1976 for whom information had been collected on complications of pregnancy. In this cohort there were 1,626 cases of breast cancer reported to the Israel Cancer Registry before January 1, 2005 and 410 cases of gestational diabetes recorded from… Expand
A Linked-Registry Study of Gestational Factors and Subsequent Breast Cancer Risk in the Mother
TLDR
It is suggested that multiple gestation pregnancies are protective, whereas delivering larger infants increases risk for later development of maternal breast cancer, in postmenopausal women associated with parity. Expand
Gestational diabetes and risk of breast cancer before age 55 years.
TLDR
It is suggested that the well-established protective effect of parity on risk of ER-positive breast cancer persists even for pregnancies complicated by GDM, and the hypothesis that GDM is a risk factor for breast cancer in young women is not supported. Expand
Gestational diabetes and risk of incident primary cancer: a large historical cohort study in Israel
TLDR
Pregnant women aged 15–50 years who underwent 50-g glucose challenge tests between 13 March 1995 and 27 May 2009, without history of malignancy, diabetes, and infertility, were included and GDM was associated with an increased risk of pancreatic cancer and hematologic malignancies. Expand
The association between a history of gestational diabetes mellitus and future risk for female malignancies
TLDR
Patients with a history of GDM have an increased risk for future breast, ovarian, and uterine malignancies, including ovarian, uterine, and breast cancer. Expand
Pregnancy-related characteristics and breast cancer risk
TLDR
N&V during pregnancy was inversely associated with breast cancer risk, and did not differ by menopausal status or breast cancer subtype including estrogen receptor and HER2 expression status. Expand
Evaluation of the Association between Gestational Diabetes Mellitus at First Pregnancy and Cancer within 10 Years Postpartum Using National Health Insurance Data in South Korea
TLDR
It is suggested that GDM is associated with the incidence of cancer, particular thyroid cancer, in women who had their first delivery between 2004 and 2005, and the Cox proportional hazards model was adopted. Expand
Incidence and relative risk for developing cancers in women with gestational diabetes mellitus: a nationwide cohort study in Taiwan
TLDR
Women with GDM have a higher risk of developing cancers and cancer screening is warranted in women with G DM, and future research should be aimed at establishing whether this association is causal. Expand
Association between gestational diabetes mellitus and subsequent risk of cancer: a systematic review of epidemiological studies.
TLDR
Although GDM increases the risk of certain types of cancer, these results should be interpreted with caution becuase of some methodological flaws. Expand
Pregnancy characteristics and maternal breast cancer risk: a review of the epidemiologic literature
TLDR
The most consistent findings in a generally sparse literature are that multiple births and preeclampsia may modestly reduce breast cancer risk and additional research is needed to elucidate associations between pregnancy characteristics, related hormonal profiles, and breast cancerrisk. Expand
The association between gestational diabetes mellitus and cancer in women: A systematic review and meta-analysis of observational studies.
  • Y. Wang, P. Yan, +4 authors Z.-J. Zhang
  • Medicine
  • Diabetes & metabolism
  • 2020
TLDR
GDM is associated with a greater risk of cancer in women, including breast, thyroid, stomach and liver cancers, but not in other regions, and also with thyroid cancer. Expand
...
1
2
3
4
...

References

SHOWING 1-10 OF 36 REFERENCES
Pregnancy Characteristics and Maternal Risk of Breast Cancer
TLDR
The data provide little support for the hypothesis that pregnancy hormone levels are associated with subsequent maternal risk of breast cancer in young women, although there is some evidence for reductions in risk for toxemia. Expand
Diabetes mellitus and breast cancer: a retrospective population-based cohort study
TLDR
A small but significant increase in incident breast cancer in a predominantly postmenopausal population of women with diabetes, when compared to women without diabetes, supports the possibility that insulin resistance or some other aspect of type 2 diabetes may promote breast cancer. Expand
Risk of endometrial and breast cancer in patients with diabetes mellitus
TLDR
It is concluded that compared with the general population, patients with diabetes mellitus have an increased incidence of endometrial and breast cancers. Expand
Selected medical conditions and risk of breast cancer.
TLDR
While most examined conditions seemed unrelated to breast cancer risk, the association with late-onset diabetes is of special interest as it suggests a role of hyperinsulinaemia and insulin resistance in breast cancer promotion and points to preventive lifestyle modifications. Expand
Race/ethnicity and other risk factors for gestational diabetes.
TLDR
Orientals, first generation Hispanics, women from the Indian subcontinent and the Middle East, those with a history of infertility, and low socioeconomic status women are at an increased risk for gestational diabetes. Expand
Type 2 diabetes and subsequent incidence of breast cancer in the Nurses' Health Study.
TLDR
Women with type 2 diabetes may have a slightly increased risk of breast cancer, and hyperinsulinemia may promote mammary carcinogenesis. Expand
Gestational diabetes and the incidence of type 2 diabetes: a systematic review.
TLDR
Differences in rates of progression between ethnic groups was reduced by adjustment for various lengths of follow-up and testing rates, so that women appeared to progress to type 2 diabetes at similar rates after a diagnosis of GDM. Expand
Breast cancer risk in young women and history of selected medical conditions.
TLDR
Generally null results from this large, population-based study support results from previous studies in providing reassurance that women with a history of several common medical conditions do not appear to be at an increased risk of breast cancer at a young age. Expand
Gestational Diabetes Mellitus: Influence of Race on Disease Prevalence and Perinatal Outcome in a U.S. Population
TLDR
The results suggest that race as well as maternal age and degree of obesity must be taken into account when comparing the prevalence of GDM in different populations and assessing the impact of specific therapeutic interventions on perinatal outcome. Expand
Adult Weight Change and Risk of Postmenopausal Breast Cancer
TLDR
It is suggested that weight gain during adult life, specifically since menopause, increases the risk of breast cancer among postmenopausal women, whereas weight loss afterMenopause is associated with a decreased risk of Breast cancer. Expand
...
1
2
3
4
...