Gestational diabetes alters human placental vascular responses to changes in oxygen tension.

@article{Figueroa1993GestationalDA,
  title={Gestational diabetes alters human placental vascular responses to changes in oxygen tension.},
  author={Reinaldo Figueroa and Haider A. Omar and Nergesh A Tejani and Michael S. Wolin},
  journal={American journal of obstetrics and gynecology},
  year={1993},
  volume={168 5},
  pages={
          1616-22
        }
}
OBJECTIVE Our objective was to study tone responses caused by hypoxia, reoxygenation, and hydrogen peroxide in human placental vessels from gestational diabetic and normal term pregnancies. STUDY DESIGN Isolated placental arteries and veins from women with well-controlled gestational diabetic and uncomplicated term pregnancies were precontracted with U46619 under 5% oxygen/5% carbon dioxide/balance nitrogen (PO2 35 to 38 torr) and then exposed to hypoxia (95% nitrogen/5% carbon dioxide… CONTINUE READING
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