Gestational changes in prostaglandin production by ovine fetal trophoblast cells.

@article{Risbridger1985GestationalCI,
  title={Gestational changes in prostaglandin production by ovine fetal trophoblast cells.},
  author={Gail P Risbridger and C M Leach Harper and M. H. Franco Wong and Geoffrey D. Thorburn},
  journal={Placenta},
  year={1985},
  volume={6 2},
  pages={117-25}
}
The effect of gestational age on the synthesis of prostaglandins (PG) by isolated preparations of uninucleate and binucleate cells of the ovine placentome has been investigated. PG synthesis by the cells was dependent upon cell number in a linear manner, and was significantly inhibited by indomethacin, but not affected by the addition of exogenous arachidonic acid. The net output of PG by the cells increased progressively with increasing gestational age of the ewe from 35 to 145 days… CONTINUE READING