Gestational Exposure of Mice to Secondhand Cigarette Smoke Causes Bronchopulmonary Dysplasia Blocked by the Nicotinic Receptor Antagonist Mecamylamine

@inproceedings{Singh2013GestationalEO,
  title={Gestational Exposure of Mice to Secondhand Cigarette Smoke Causes Bronchopulmonary Dysplasia Blocked by the Nicotinic Receptor Antagonist Mecamylamine},
  author={Shashi Prabha Singh and Sravanthi Gundavarapu and Kevin R. Smith and Hitendra S Chand and Ali I Saeed and Neerad C. Mishra and Julie Hutt and Edward G. Barrett and Matloob Husain and Kevin S. Harrod and Raymond J Langley and Mohan L. Sopori},
  booktitle={Environmental health perspectives},
  year={2013}
}
BACKGROUND Cigarette smoke (CS) exposure during gestation may increase the risk of bronchopulmonary dysplasia (BPD)-a developmental lung condition primarily seen in neonates that is characterized by hypoalveolarization, decreased angiogenesis, and diminished surfactant protein production and may increase the risk of chronic obstructive pulmonary disease. OBJECTIVE We investigated whether gestational exposure to secondhand CS (SS) induced BPD and sought to ascertain the role of nicotinic… CONTINUE READING
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