Germline mutation in the aryl hydrocarbon receptor interacting protein gene in familial somatotropinoma.

@article{Toledo2007GermlineMI,
  title={Germline mutation in the aryl hydrocarbon receptor interacting protein gene in familial somatotropinoma.},
  author={Rodrigo de Toledo and Delmar Muniz Lourenço and Bernardo Liberman and Malebranche Berardo Carneiro da Cunha-Neto and Maria Gabriela Cavalcanti and Cinthia Bachir Moys{\'e}s and S{\'e}rgio Pereira de Almeida Toledo and Patricia L M Dahia},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2007},
  volume={92 5},
  pages={1934-7}
}
CONTEXT Acromegaly is usually sporadic, but familial cases occur in association with several familial pituitary tumor syndromes. Recently mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene were associated with familial pituitary adenoma predisposition. OBJECTIVE The objective of the study was to investigate the status of AIP in a pituitary tumor predisposition family. SETTINGS The study was conducted at a nonprofit academic center and medical centers. PATIENTS… CONTINUE READING