Germline CDKN2A Mutation Status and Survival in Familial Melanoma Cases.

@article{Helgadottir2016GermlineCM,
  title={Germline CDKN2A Mutation Status and Survival in Familial Melanoma Cases.},
  author={Hildur Helgadottir and Veronica H{\"o}iom and Rainer Tuominen and Kari Nielsen and G{\"o}ran B. J{\"o}nsson and H{\aa}kan Olsson and Johan Hansson},
  journal={Journal of the National Cancer Institute},
  year={2016},
  volume={108 11}
}
BACKGROUND Germline mutations in CDKN2A have been associated with increased risk of melanoma and tobacco-related cancers in respiratory and upper digestive tissues. In CDKN2A wild-type (wt) melanoma families, other known high-risk, melanoma-predisposing mutations are rare, and no increased risk has been observed for nonskin cancers in this group. This study… CONTINUE READING