Germline BRCA1 185delAG mutations in Jewish women with breast cancer.

@article{Offit1996GermlineB1,
  title={Germline BRCA1 185delAG mutations in Jewish women with breast cancer.},
  author={Kenneth Offit and Teresa A. Gilewski and Peter McGuire and Alice E. Schluger and Heather Hampel and Karen L. Brown and Jeff Swensen and Susan L. Neuhausen and Mark Skolnick and Larry Norton and David E. Goldgar},
  journal={Lancet},
  year={1996},
  volume={347 9016},
  pages={1643-5}
}
BACKGROUND We aimed to find out the proportion of breast cancers in Ashkenazi Jewish women attributable to the frameshift mutation at position 185 involving the deletion of adenine and guanine (185delAG) in the breast cancer gene BRCA1. METHODS We studied 107 Ashkenazi Jewish women with breast cancer seen at medical oncology and genetic counseling clinics in New York over a three and a half year period beginning in 1992. 80 of the women were diagnosed before age 42 years; the other 27 were… CONTINUE READING
30 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 30 extracted citations

Similar Papers

Loading similar papers…