Germinal centers in the bone marrow.


Germinal centers (GCs) in the marrow have been described, but not systematically studied. Twelve cases from the axial skeleton from patients aged 29-80 years were examined. The male female ratio was 1:5, and the yearly incidence was 0.8% of bone marrow specimens. Most patients were anemic (mean hematocrit 34%); five had eosinophilia. When both clots and… (More)


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