Germicidin, an autoregulative germination inhibitor of Streptomyces viridochromogenes NRRL B-1551.

@article{Petersen1993GermicidinAA,
  title={Germicidin, an autoregulative germination inhibitor of Streptomyces viridochromogenes NRRL B-1551.},
  author={Frieddrich Petersen and Hans Z{\"a}hner and J{\"o}rg W. Metzger and Stefan Freund and Robert P Hummel},
  journal={The Journal of antibiotics},
  year={1993},
  volume={46 7},
  pages={1126-38}
}
During germination spores of Streptomyces viridochromogenes NRRL B-1551 excrete a compound, germicidin, which has an inhibitory effect on the germination of its own arthrospores at a concentration as low as 200 pM (40 pg/ml). At higher concentrations germicidin inhibits porcine Na+/K(+)-activated ATPase and retards the germination of the cress Lepidium sativum. Germicidin is the first known autoregulative inhibitor of spore germination in the genus Streptomyces and was isolated from the… CONTINUE READING