Germ cells from mouse and human embryonic stem cells.

@article{Aflatoonian2006GermCF,
  title={Germ cells from mouse and human embryonic stem cells.},
  author={Behrouz Aflatoonian and Harry Moore},
  journal={Reproduction},
  year={2006},
  volume={132 5},
  pages={699-707}
}
Mammalian gametes are derived from a founder population of primordial germ cells (PGCs) that are determined early in embryogenesis and set aside for unique development. Understanding the mechanisms of PGC determination and differentiation is important for elucidating causes of infertility and how endocrine disrupting chemicals may potentially increase susceptibility to congenital reproductive abnormalities and conditions such as testicular cancer in adulthood (testicular dysgenesis syndrome… CONTINUE READING

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[Human embryo stem cells and gametes: science fiction or near future?].

Gynecologie, obstetrique & fertilite • 2008
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