Germ cells enter meiosis in a rostro-caudal wave during development of the mouse ovary.

@article{Bullejos2004GermCE,
  title={Germ cells enter meiosis in a rostro-caudal wave during development of the mouse ovary.},
  author={Monica Bullejos and Peter Koopman},
  journal={Molecular reproduction and development},
  year={2004},
  volume={68 4},
  pages={422-8}
}
Germ cells in the mouse embryo remain undifferentiated until about 13.5 days post-coitum (dpc), when male germ cells enter mitotic arrest and female germ cells enter meiosis. The molecular signals and transcriptional control mechanisms governing the differential fate of germ cells in males and females remain largely unknown. In order to gain insights into the behavior of germ cells around this period and into likely mechanisms controlling entry into meiosis, we have studied by wholemount in… CONTINUE READING

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In order to gain insights into the behavior of germ cells around this period and into likely mechanisms controlling entry into meiosis , we have studied by wholemount in situ hybridization the expression pattern of two germ cell - specific markers , Oct4 and Sycp3 , during mouse fetal gonad development .
In order to gain insights into the behavior of germ cells around this period and into likely mechanisms controlling entry into meiosis , we have studied by wholemount in situ hybridization the expression pattern of two germ cell - specific markers , Oct4 and Sycp3 , during mouse fetal gonad development .
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