Germ cell-less encodes a cell type-specific nuclear pore-associated protein and functions early in the germ-cell specification pathway of Drosophila.

@article{Jongens1994GermCE,
  title={Germ cell-less encodes a cell type-specific nuclear pore-associated protein and functions early in the germ-cell specification pathway of Drosophila.},
  author={Thomas A. Jongens and Larry D. Ackerman and Jason R. Swedlow and Lily Yeh Jan and Yuh Nung Jan},
  journal={Genes & development},
  year={1994},
  volume={8 18},
  pages={2123-36}
}
The maternally supplied plasm at the posterior pole of a Drosophila embryo contains determinants that specify both the germ-cell precursors (pole cells) and the posterior axis. One pole plasma component, the product of the germ cell-less gene, has been found to be required for specification of pole cells, but not posterior somatic cells. Mothers with reduced levels of gcl give rise to progeny that lack pole cells, but are otherwise normal. Mothers overexpressing gcl, on the other hand, produce… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 46 extracted citations

Similar Papers

Loading similar papers…